A 72yo man is receiving chemotherapy for SCLC. He had his 4th tx 8 days ago. He has a cough
with some green sputum but feels well. Temp=37.6C. Chest exam = few coarse crepitations in
the right base. HR=92bpm. CBC: Hgb=12.5g/dL, WBC=1.1, Neutrophils=0.6, Plt=89. Sputum,
urine and blood culture sent to microbiology. What is the most appropriate management?
a. Broad spectrum antibiotics IV
b. Broad spectrum antibiotics PO
c. GCSF
d. Postpone tx until bacteriology results available
e. Reassure and send home
answer: A .........by logic empiral antibiotics IV (high risk pt prefer iv vs oral) til results of microbiology then sensitive ABs
what is GCSF?
Granulocyte-colony stimulating factor (G-CSF or GCSF),
also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein
that stimulates the bone marrow to produce granulocytes and stem cells
and release them into the bloodstream.
used to treat leukopenia in chemo patients
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