Generalized edema, proteinura, 15yo (173/1700)

A 15yo boy presents with generalized edema. His urinalysis reveals protein +++, eGFR =110.
What is the most likely dx?

a. IgA nephropathy
b. Membranous nephropathy
c. Minimal change disease
d. PSGN
e. Lupus nephritis



























answer C

MCGN = most common cause of nephrotic syndrome in children
Membranous = most common cause of nephrotic syndrome in adults
IgA nephropathy = nephritic syndrome
PSGN = nephritic syndrome

Nephrotic syndrome: PALE
Proteinuria > marked
Albumin low
Lipids high
Edema

Nephritic syndrome: PHAROH
Proteinuria mild
Hematuria
Azotemia = high BUN
RBC casts
Oliguria
HTN