Discharge, dysuria, dysparenia (330/1700)

A lady presents with abdominal pain, dysuria, dyspareunia and vaginal discharge. What is your
next step?

a. Laparoscopy
b. High vaginal swab
c. Hysteroscopy
d. Laparotomy
e. US































answer: B

discharge and the symptoms given point to PID, laporoscopy is the GOLD standard but next step would be a swab for c+s which will help us choose the best AB regimen



PID
Clinical Presentation
• up to 2/3 asymptomatic: many subtle or mild symptoms
common
·        fever >38.3ºC
·        lower abdominal pain and tenderness
·        abnormal discharge: cervical or vaginal
• uncommon
·        N/V
·        dysuria
·        AUB
chronic disease (often due to chlamydia)
·        constant pelvic pain
·        dyspareunia
·        palpable mass
·        very difficult to treat, may require surgery

Investigations
• blood work
·        β-hCG (must rule out ectopic pregnancy), CBC, blood cultures if suspect septicemia
• urine R&M
• speculum exam, bimanual exam
·        vaginal swab for Gram stain, C&S
·        cervical cultures for N. gonorrhoeae, C. trachomatis
·        endometrial biopsy will give definitive diagnosis (rarely done)
• ultrasound
·        may be normal
·        free fluid in cul-de-sac
·        pelvic or tubo-ovarian abscess
·        hydrosalpinx (dilated fallopian tube)
• laparoscopy (gold standard)
·        for definitive diagnosis: may miss subtle inflammation of tubes or endometritis


Treat PID with FOXY DOXY
(cefoxitin + doxycycline)

If the risk of gonococcal infection is low, prescribe any of the following:

·        Oral levofloxacin/ofloxacin 400 mg twice daily plus oral metronidazole 400 mg twice daily, both for 14 days.
·        Ceftriaxone 500 mg as a single IM dose, followed by oral doxycycline 100 mg twice daily plus oral metronidazole 400 mg twice daily, both for 14 days.
·        Ceftriaxone 500 mg as a single IM dose, followed by oral azithromycin 1 g per week for 2 weeks. Not recommended.

If the risk of gonococcal infection is high (for example the woman's partner has gonorrhoea, her symptoms and signs are clinically severe, or she has had sexual contact whilst abroad), prescribe either of the following:

·        Ceftriaxone 500 mg as a single IM dose, followed by oral doxycycline 100 mg twice daily plus oral metronidazole 400 mg twice daily, both for 14 days

N.B.
A regimen of metronidazole and doxycycline without intramuscular ceftriaxone is not recommended.

Oral cefixime 400 mg as a single dose (off-label use) can be used as an alternative to ceftriaxone 500 mg in the above regimens.

Regimens containing ofloxacin or azithromycin are not recommended in women at high risk of gonococcal PID.

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