ring form plasmodium with schuffners dots in RBCs. What is the drug to eradicate this infection?
a. Doxycycline
b. Mefloquine
c. Proguanil
d. Quinine
e. Artesonate
answer: B
Schüffner's dots refers to a hematological finding, exclusively found in Plasmodium ovale and Plasmodium vivax
Treatment and Prevention of malaria
• P. vivax, P. ovale:
chloroquine (and primaquine to eradicate liver forms)
• P. vivax, chloroquine
resistant:
primaquine with quinine and doxycycline
or tetracycline
or mefloquine
• P. malariae, P. knowlesi:
chloroquine
• P. falciparum: most
areas of the world show chloroquine resistance – check
local resistance patterns
-artemisinin combination therapy
(e.g. artesunate + doxycycline or clindamycin or atovaquone/proguanil)
- atovaquone/proguanil combination
(Malarone)
-quinine plus doxycycline,
tetracycline, or clindamycin
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