Lung cancer histopathology (910/1700)

Pt with a long hx of smoking is now suffering from bronchial ca. histology reveals there are
sheets of large polygonal or giant MNC. What is the most likely dx?
a. Squamous cell ca
b. Small cell ca
c. Adenocarcinoma
d. Large cell ca
e. Oat cell ca

































 answer: D

Central:
Squamous cell carcinoma
Keratin, intercellular bridges


Small cell
Oat cell, neuroendocrine

Peripheral:
Adenocarcinoma
Glandular, mucin producing

Large cell
anaplastic, undifferentiated sheets/nests of polygonal/multinuclear cells 

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