Enuresis (291/1700)

A 6yo girl started wetting herself up to 6x/day. What is the most appropriate tx?
a. Sleep alarms
b. Desmopressin
c. Reassure
d. Behavior training
e. Imipramine
































answer: D






Primary Nocturnal Enuresis
• definition: involuntary loss of urine at night, bladder control has never been attained
• etiology: developmental disorder or maturational lag in bladder control while asleep
• management
-        time and reassurance if <6years
-        behavior modification (voiding prior to sleep)
-        conditioning: “wet” alarm wakes child upon voiding {first line <7years}
-        medications (considered second line therapy, may be used for sleepovers/camp):
Desmopressin (1st line >7years} {2nd line <7years or if alarm inappropriate, or rapid control needed}
imipramine (rarely used, lethal if overdose, cholinergic side effects) {resistant cases}

Secondary Enuresis
definition: involuntary loss of urine at night, develops after child has sustained period of bladder control (>6 mo)
etiology: inorganic regression due to stress or anxiety (e.g. birth of sibling, significant loss, family discord), focused on other activities, secondary to organic disease (UTI, DM, DI, neurogenic bladder, CP, seizures, pinworms)
management: treat underlying cause

Diurnal Enuresis
definition: daytime wetting (60-80% also wet at night)
etiology: micturition deferral (holding urine until last minute) due to psychosocial stressor (e.g.
shy), structural anomalies (e.g. ectopic ureteral site, neurogenic bladder), UTI, constipation, CNS disorders, DM
management: treat underlying cause,
Behavioral (scheduled toileting, double voiding, good bowel program)
Desmopressin if >7years

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