a. Atenolol
b. Salbutamol
c. Salmetrol
d. Ipratropium bromide
e. Cocaine
answer A
non selective B blockers b1/b2 theorectically can cause bronchospasm as they are the opposite of B2 agonists which cause bronchodilation, however cardio selective B1 blockers have a negligible effect on b2 receptors, so they won't cause bronchospasm
Clinical Uses | ||||||
Class/Drug | HTN | Angina | Arrhy | MI | CHF | Comments |
Non-selective β1/β2 | ||||||
carteolol | X | ISA; long acting; also used for glaucoma | ||||
carvedilol | X | X | α-blocking activity | |||
labetalol | X | X | ISA; α-blocking activity | |||
nadolol | X | X | X | X | long acting | |
penbutolol | X | X | ISA | |||
pindolol | X | X | ISA; MSA | |||
propranolol | X | X | X | X | MSA; prototypical beta-blocker | |
sotalol | X | several other significant mechanisms | ||||
timolol | X | X | X | X | primarily used for glaucoma | |
β1-selective | ||||||
acebutolol | X | X | X | ISA | ||
atenolol | X | X | X | X | ||
betaxolol | X | X | X | MSA | ||
bisoprolol | X | X | X | X | ||
esmolol | X | X | ultra short acting; intra or postoperative HTN | |||
metoprolol | X | X | X | X | X | MSA |
nebivolol | X | relatively selective in most patients; vasodilating (NO release) |
So the correct answer is E cocaine as atenolo is selective
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