Loss of vision (378/1700)

A 32yo woman had progressive decrease in vision over 3yrs. She is now dx as almost blind. What
would be the mechanism?
a. Cataract
b. Glaucoma
c. Retinopathy
d. Uveitis
e. Keratitis


































answer: C

  • cataract, age related
  • glaucoma, open angle(famility history or htn, dm, hypothyroidism, loss of central vision is late) closed angle(small eye, old age)
  • uveitis (acute red eye) 
  • keratitis (acute red eye)

Retinitis pigmentosa
The age of onset, rate of progression, eventual visual loss
and associated ocular features are frequently related to
the mode of inheritance. RP may occur as an isolated
sporadic disorder, or be inherited as AD, AR or XL. Many
cases are due to mutation of the rhodopsin gene. XL is the
least common but most severe form and may result in complete
blindness by 3rd or 4th decade.

Clinical Features
• night blindness, decreased peripheral vision (“tunnel vision”), decreased central vision (macular
changes), glare (from cataract)
Investigations
• fundoscopy: areas of “bone-spicule” pigment clumping in mid-periphery of retina, narrowed
retinal arterioles, pale optic disc
• electrophysiological tests: electroretinography (ERG) and electrooculography (EOG) assist in
diagnosis




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